Image processing protocols and genetic analysis protocols for various ENIGMA projects are listed to the right.
These protocols are meant as a guide. Please direct specific troubleshooting queries to the ENIGMA support group at enigma@ini.usc.edu.
All protocols are public and you are welcome to use them for any project. If you are using the ‘ENIGMA1′ protocols, please cite Stein et al., Nature Genetics, 2012. If you are using the ‘ENIGMA2′ protocols, please cite Hibar et al., Nature, 2015. For projects outside of ENIGMA, please include a reference to the ENIGMA website (http://enigma.ini.usc.edu/) so that your readers and reviewers know about our work.
These protocols are subject to changes and improvements. Please check the ENIGMA GitHub page for amendments and updates!
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ENIMGA sMRI Imaging Protocols
Detailed structural MRI imaging analysis protocols, including subcortical VOLUME extraction, subcortical SHAPE analysis, cortical thickness and surface area analysis
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ENIGMA DTI Imaging Protocols
Detailed diffusion tensor imaging protocols for the ENIGMA DTI based projects.
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ENIGMA Subcortical Shape Protocols
Detailed protocols for ENIGMA Shape analyses.
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Genetics Protocols
Genetic analysis protocols for ENIGMA1, ENIGMA2 and ENIGMA-Cortex and DTI.